Human Leukocyte Antigen Class II associations in late‐onset Myasthenia Gravis

Human Leukocyte Antigen Class I and II Variants in Yemeni Patients with Chronic Renal Failure

Background: Human leukocyte antigens (HLAs) are found to be significant genetic factors concerning the susceptibility of an individual to certain diseases. Objective: To determine the association between variants of class I (A and B) and class II (DRB1) HLA alleles and chronic renal failure (CRF), compared with healthy controls, in Yemen. Methods: A case-control study in the Urology and Nephrol...

P-164: Human Leukocyte Antigen Class Ib and Pregnancy Success

Background: During pregnancy, the maternal immune system is in close contact with cells and tissue from the semiallogenic fetus .The Human Leucocyte Antigen (HLA) class Ib molecules, HLA-E, -F and -G, are expressed at the materno-fetal interface. Because of the apparent immunoregulatory functions of these proteins, they may be involved in successful acceptance of the semi-allogenic fetus during...

Genetic associations in myasthenia gravis

O-5 Novel HLA II associations in myasthenia gravis

O-3 Clinical features and outcome measures during 1 year enzyme replacement therapy in late onset GSD II patients C. Angelini, C. Semplicini, E. Pegoraro, M. Filosto, G. Marrosu R. Piras, T. Mongini, L. Vercelli, P. Tonin, S. Servidei, R. Di Giacopo, G. Crescimanno, S. Ravaglia, A. Toscano, O. Musumeci, G. Siciliano, G. Ricci, Di Iorio, F. Cipullo, M. Moggio, G. Comi, V. Lucchini, L. Morandi 1 ...

Analysis of Human Leukocyte Antigen class II Gene Polymorphism in Iranian Patients with Papillon-Lefevre Syndrome: a Family Study

Background: Papillon-Lefevre syndrome (PLS) is a rare autosomal recessive disorder characterized by palmoplantar hyperkeratosis and early development of aggressive pe-riodontitis. Although cathepsin C (CTSC) gene mutations have been established in about 70-80% of PLS patients, it is assumed that the patients may have dysfunctioning of immune defense mechanisms. Objective: To assess the associat...